产品货号：
Z12878
中文名称：
CD1D抗体
英文名称：
Anti-CD1D Antibody
产品规格：
50μl|100μl|150μl
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-CD1D Antibody |
| 指标别名 | CD1A;CD1D;CD1d molecule;R3;R3G1 |
| 克隆性 | Polyclonal |
| 检验物种 | human |
| 应用范围 | WB,IHC |
| 基因名称 | CD1D |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | A synthetic peptide corresponding to a sequence at the N-terminus of human CD1d(76-92aa FSDQQWETLQHIFRVYR). |
| 实际分子量 | 40KD |
| 成分 | 500μg/mL antibody with PBS，0.02% NaN3,1mg BSA and 50% glycerol. |
| 纯化方式 | Immunogen affinity purified. |
| 浓度 | 500μg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 12 months from date of receipt，-20℃ as supplied.6 months 2 to 8℃ after reconstitution.Avoid repeated freezing and thawing. |
| 背景资料 | CD1D(CD1d molecule) also known as R3G1,Antigen-presenting glycoprotein CD1d,R3G1,CD1D,is the sole group-2 member of the CD1 family of major histocompatibility(MHC)-like glycoproteins.Expressed on the surface of various human antigen-presenting cells.They are related to the class I MHC molecules,and are involved in the presentation of lipid antigens to T cells.It is the only member of the group 2 CD1 molecules.CD1d presented lipid antigens activate a special class of T cells,known as Natural Killer T(NKT) cells.When activated,NKT cells rapidly produce Th1 and Th2 cytokines,typically represented by interferon-gamma and IL-4 production.Jayawardena-Wolf et al.described 2 different pathways of Cd1d trafficking to endosomal compartments in mouse cells.A tyrosine-based motif governs recycling between the plasma membrane and the endosome,while Cd1d associates,like major histocompatibility complex class II antigens,with the invariant chain,or II,in the endoplasmic reticulum.Both pathways enhance antigen presentation to Cd1d-restricted natural killer T cells. |
| Uniprot ID | P15813 |
| 推荐配套试剂 | Biorab recommends Enhanced Chemiluminescent Kit with anti-Rabbit IgG (ZN1926) for Western blot,and HRP Conjugated anti-Rabbit IgG Super Vision Assay Kit (ZN1865) for IHC(P).*Blocking peptide可以联系我们购买。 |
| 基因名全称 | CD1d molecule |
| 蛋白名全称 | Antigen-presenting glycoprotein CD1d |
| 推荐稀释比 | Western blot(WB) 1:500～2000 Immunohistochemistry in paraffin section (IHC) 1:50～400 (Boiling the paraffin sections in 10mM citrate buffer,pH6.0,or PH8.0 EDTA repair liquid for 20 mins is required for the staining of formalin/paraffin sections.) Optimal working dilutions must be determined by end user. |
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